Folic acid-

Folic acid acts as a coenzyme for transfer and utilization of formate C1 fragment in the form of tetrahydrofolic acid. It is used in the treatment of macrocytic anaemia. It takes part in purine nucleotide synthesis and thymidylate synthesis. Folic acid consist of pteridine nucleus, P aminobenzoic acid and glutamic acid.

Physiological function of vitamin C-

1) It is involved in oxidation-reduction of the cell. It is a donor of reducing equivalents in certain key reaction.
2) It is involved in the conversion of folic acid to the active form, tetrahydrofolic derivative.
3) It is involved in tyrosine metabolism i.e. oxidation of p-hydroxyphenyl pyruvate to homogentisate.
4) It is used in absorption of iron by converting the inorganic ferric iron to the ferrous form.
5) It is essential for the activity of fibroblasts, osteoblasts and odonoblasts. It causes hydroxylation of proline in collagen synthesis.